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          • Primary Antibodies ›
          • NVL Antibodies

          Invitrogen

          NVL Polyclonal Antibody

          View all (10) NVL antibodies

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          Cite NVL Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          NVL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          NVL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          NVL Antibody (PA5-55796) in IHC (P)

          Immunohistochemical analysis of NVL in human esophagus using NVL Polyclonal Antibody (Product # PA5-55796) shows moderate nuclear and nucleolar positivity in squamous epithelial cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NVL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NVL Antibody in Western Blot (WB)
          NVL Antibody in Western Blot (WB)
          NVL Polyclonal Antibody

          Product Details

          PA5-55796

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human NVL. Recombinant protein control fragment (Product #RP-94303).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2644911

          Product Specific Information

          Immunogen sequence: LESDMKRKGK LKNKGSKRKK EDLQEVDGEI EAVLQKKAKA RGLEFQISNV KFEDVGGNDM TLKEVCKMLI HMRHPEVYHH LG

          Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 78%.

          Target Information

          Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Nuclear valosin-containing protein-like; nuclear VCP-like protein; NVLp; unnamed protein product

          View more View less

          Gene Aliases: 1200009I24Rik; NVL; NVL2

          View more View less

          UniProt ID: (Human) O15381, (Mouse) Q9DBY8

          View more View less

          Entrez Gene ID: (Human) 4931, (Rat) 289323, (Mouse) 67459

          View more View less

          Function(s)
          nucleotide binding RNA binding protein binding ATP binding ATPase activity macromolecular complex binding preribosome binding poly(A) RNA binding
          Process(es)
          rRNA processing positive regulation of protein binding positive regulation of telomere maintenance ribosome biogenesis ribosomal large subunit biogenesis regulation of protein localization to nucleolus telomerase holoenzyme complex assembly biological_process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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