DST (disuccinimidyl tartrate)
DST (disuccinimidyl tartrate)
Citas y referencias (4)
Thermo Scientific™

DST (disuccinimidyl tartrate)

El DST (también llamado disucinimidilo tartrato) Thermo Scientific Pierce es un entrecruzador soluble en agua que contiene extremos de ésterMás información
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Número de catálogoCantidad
2058950 mg
Número de catálogo 20589
Precio (CLP)
339.054
Each
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Cantidad:
50 mg
Pedido a granel o personalizado
Precio (CLP)
339.054
Each
Añadir al carro de la compra
El DST (también llamado disucinimidilo tartrato) Thermo Scientific Pierce es un entrecruzador soluble en agua que contiene extremos de éster de NHS reactivos con aminas alrededor de un brazo espaciador de 4 átomos, cuyo diol central se puede escindir con oxidación de periodato.

Características del disucinimidilo tartrato:

• Grupos reactivos: Éster de NHS (ambos extremos)
• Reactivo a: grupos aminos (aminas primarias)
• Soluble en DMSO o DMF a una concentración de ∼10 mM (3 mg/ml)
• Escindible por metaperiodato sódico (n.° de referencia 20504)
• Ideal para aplicaciones en las que se desea una capacidad de escisión de entrecruzamiento sin alterar los enlaces de disulfuro de proteínas

Referencias de producto:

Guía de aplicación entrecruzada: búsqueda de referencias bibliográficas recientes para este producto.

Productos relacionados
DST (disucinimidilo tartrato)
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Permeabilidad celularSí
DescripciónDST
FormularioPolvo
Método de etiquetadoEtiqueta química
Peso molecular344.23
PegiladoNo
Línea de productosPierce
Cantidad50 mg
Fracción reactivaÉster NHS
Condiciones de envíoAmbiente
SolubilidadAgua
Longitud del brazo del separador4,0 Å
Soluble en aguaSí
Reactividad químicaAmina-amina
CleavablePor periodato
Tipo de enlace cruzadoHomobifuncionales
FormatoEstándar
Tipo de productoEntrecruzador
SeparadorCorto (< 10 Å)
Unit SizeEach
Contenido y almacenamiento
Tras su recepción, almacenar desecado a 4 °C.

Preguntas frecuentes

Can you provide the shelf-life for DST (disuccinimidyl tartrate)?

DST (disuccinimidyl tartrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

Citations & References (4)

Citations & References
Abstract
Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs.
Authors:Alian A, Griner SL, Chiang V, Tsiang M, Jones G, Birkus G, Geleziunas R, Leavitt AD, Stroud RM
Journal:Proc Natl Acad Sci U S A
PubMed ID:19416821
HIV-1 integration into the host cell genome is a multistep process catalyzed by the virally-encoded integrase (IN) protein. In view of the difficulty of obtaining a stable DNA-bound IN at high concentration as required for structure determination, we selected IN-DNA complexes that form disulfide linkages between 5'-thiolated DNA and several ... More
Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Authors:Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J
Journal:Proc Natl Acad Sci U S A
PubMed ID:19556541
Mutations in PKD1 and TRPP2 account for nearly all cases of autosomal dominant polycystic kidney disease (ADPKD). These 2 proteins form a receptor/ion channel complex on the cell surface. Using a combination of biochemistry, crystallography, and a single-molecule method to determine the subunit composition of proteins in the plasma membrane ... More
Enhanced tissue penetration-induced high bonding strength of a novel tissue adhesive composed of cholesteryl group-modified gelatin and disuccinimidyl tartarate.
Authors:Matsuda M, Ueno M, Endo Y, Inoue M, Sasaki M, Taguchi T
Journal:Colloids Surf B Biointerfaces
PubMed ID:22088758
The aim of this study was to evaluate the effect of cholesteryl group content on the bonding strength of a novel tissue adhesive composed of cholesteryl group-modified geletin (CholGltn) and disuccinimidyl tartarate (DST). The bonding strength of this tissue adhesive with fresh arterial media reached a maximum at a CholGltn ... More
Arabidopsis Cor15am is a chloroplast stromal protein that has cryoprotective activity and forms oligomers.
Authors:Nakayama K, Okawa K, Kakizaki T, Honma T, Itoh H, Inaba T
Journal:Plant Physiol
PubMed ID:17384167
Many plants acquire increased freezing tolerance when they are exposed to nonfreezing temperatures of a certain duration. This process is known as cold acclimation and allows plants to protect themselves from freezing injury. A wide variety of polypeptides are induced during cold acclimation, among which is one encoded by COR15A ... More