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Invitrogen
Human EphA6, GST Tag Recombinant Protein
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Product Details
PV6339
Product Specifications
Species
Human
Expression System
Baculovirus
Amino acid sequence
561-end
Tag
GST-tag
Molecular weight
77 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris HCl, pH 7.5, with 10mM glutathione, 0.1mM PMSF, 25% glycerol, 0.1mM EDTA, 150mM NaCl, 0.25mM DTT
Contains
no preservative
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Recombinant human EPHA6 (561-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use
Related Product:
LanthaScreen™ Eu Kinase Binding Assay
Protein Form: Recombinant
The gene accession number for EphA6 is NP_001073917.2.
Target Information
EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434C1418; EHK-2; EK12; EPH homology kinase 2; EPH-like kinase 12; ephrin receptor EphA6; Ephrin type-A receptor 6; FLJ35246
Gene Aliases: EHK-2; EHK2; EK12; EPA6; EPHA6; HEK12; PRO57066
UniProt ID: (Human) Q9UF33
Entrez Gene ID: (Human) 285220
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