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Abnova
TSSK6 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 2
TSSK6 Antibody (H00083983-D01P) in WB
Western Blot analysis of TSSK6 expression in transfected 293T cell line (H00083983-T02) by TSSK6 MaxPab polyclonal antibody.
Lane 1: TSSK6 transfected lysate(30.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TSSK6 transfected lysate(30.30 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00083983-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSSK6 (NP_114426.1, 1 a.a. approximately 273 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE VCNGKLYIVM EAAATDLLQA VQRNGRIPGV QARDLFAQIA GAVRYLHDHH LVHRDLKCEN VLLSPDERRV KLTDFGFGRQ AHGYPDLSTT YCGSAAYASP EVLLGIPYDP KKYDVWSMGV VLYVMVTGCM PFDDSDIAGL PRRQKRGVLY PEGLELSERC KALIAELLQF SPSARPSAGQ VARNCWLRAG DSG
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 72; CT72; serine/threonine protein kinase SSTK; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; testis secretory sperm-binding protein Li 205a; Testis-specific serine/threonine-protein kinase 6; TSK-6; unnamed protein product
Gene Aliases: CT72; FKSG82; SSTK; TSSK4; TSSK6
UniProt ID: (Human) Q9BXA6
Entrez Gene ID: (Human) 83983
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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