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Invitrogen
Yellow Fever Virus NS4B (strain 17D vaccine) Recombinant Rabbit Monoclonal Antibody (HL2449)
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FIGURE: 1 / 2
Yellow Fever Virus NS4B (strain 17D vaccine) Antibody (MA5-56926) in ICC/IF
Immunocytochemistry analysis of Yellow Fever Virus NS4B (strain 17D vaccine) using Yellow Fever Virus NS4B (strain 17D vaccine) Recombinant Monoclonal Antibody (Product # MA5-56926) in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Yellow Fever Virus NS4B (strain 17D vaccine) antibody diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
MA5-56926
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2449
Immunogen
Full length Yellow Fever virus NS4B Protein.(strain 17D vaccine)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The NS4B protein of the Yellow Fever Virus (YFV) is a non-structural protein that plays a crucial role in the virus's replication process. As part of the viral replication complex, NS4B is involved in the formation of membrane-associated replication compartments within the host cell, which are essential for efficient viral RNA synthesis. This protein also interacts with other non-structural proteins and host factors to modulate the host's immune response, aiding in viral evasion of immune detection. Due to its integral role in the replication and immune modulation, NS4B is considered a significant target for antiviral drug development. Inhibiting NS4B function can potentially disrupt the viral replication cycle, thereby reducing viral load and disease severity. Current research is focused on understanding the precise mechanisms of NS4B's interactions and functions, which could lead to the development of novel therapeutic interventions aimed at combating yellow fever and other flavivirus infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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