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          • Primary Antibodies ›
          • pho Antibodies

          Invitrogen

          pho Polyclonal Antibody

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          Cite pho Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          pho Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          pho Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          pho Antibody (PA5-144384) in WB

          Western blot analysis of pho in recombinant protein using a dilution of 1:2,000. Samples were incubated with pho polyclonal antibody (Product # PA5-144384). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          pho Antibody in Western Blot (WB)
          pho Polyclonal Antibody

          Product Details

          PA5-144384

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Fruit fly

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Drosophila melanogaster (Fruit fly) pho protein (1-250aa )
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          3.05 mg/mL

          Amount

          305 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% Proclin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3091672

          Target Information

          Polycomb group (PcG) protein that binds to the 5'-CNGCCATNNNNG-3' sequence found in the regulatory regions of many genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Probably targets the Esc/E(z) complex to DNA. Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: CG17743-PA; CG17743-PB; peiohomeotic; PHO; pho-PA; pho-PB; pleihomeotic; pleohomeotic; Polycomb protein PHO; Polycomb protein PHO pho CG17743; polyhomeotic; Protein pleiohomeotic; RE17954p; Transcription factor YY1 homolog; zinc finger protein

          View more View less

          Gene Aliases: CG17743; Dmel\CG17743; Dmel_CG17743; dYY1; l(4)102EFc; l(4)29; l(4)BU-2; l(4)OC-1; l(4)pho; PHO; PHO/YY1; YY1

          View more View less

          UniProt ID: (Fruit fly) Q8ST83

          View more View less

          Entrez Gene ID: (Fruit fly) 43819

          View more View less

          Function(s)
          RNA polymerase II core promoter proximal region sequence-specific DNA binding DNA binding chromatin binding protein binding chromatin DNA binding sequence-specific DNA binding DNA-binding transcription factor zinc finger transcription factor C2H2 zinc finger transcription factor gene-specific transcriptional regulator
          Process(es)
          DNA topological change chromatin remodeling chromatin silencing regulation of transcription, DNA-templated negative regulation of gene expression gene silencing negative regulation of transcription, DNA-templated chromatin-mediated maintenance of transcription dendrite morphogenesis
          It has to be done as per old AB suggested Products section.

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