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Abnova
FZD3 Monoclonal Antibody (2H5)
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Product Details
H00007976-M09
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2H5
Immunogen
FZD3 (NP_059108, 55 a.a. approximately 157 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: QQTAALAMEP FHPMVNLDCS RDFRPFLCAL YAPICMEYGR VTLPCRRLCQ RAYSECSKLM EMFGVPWPED MECSRFPDCD EPYPRLVDLN LAGEPTEGAP VAV
Target Information
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; FZD3; hFz3; unnamed protein product
Gene Aliases: Fz-3; FZD3
UniProt ID: (Human) Q9NPG1
Entrez Gene ID: (Human) 7976
establishment of planar polarity
neural tube closure
hair follicle development
positive regulation of neuroblast proliferation
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
nervous system development
response to xenobiotic stimulus
Wnt signaling pathway
neuron differentiation
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
response to electrical stimulus
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
sympathetic ganglion development
commissural neuron axon guidance
motor neuron migration
negative regulation of execution phase of apoptosis
midbrain morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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