Mag-Fluo-4, AM, cell permeant - Special Packaging

Citations & References (24)

Invitrogen™

Mag-Fluo-4, AM, cell permeant - Special Packaging

Useful as intracellular mg²⁺ indicator as well as low-affinity Ca²⁺ indicator

Catalog Number	Quantity
M14206	10 x 50 μg

Catalog number M14206

Price (EUR)

678,00

Quantity:

10 x 50 μg

Price (EUR)

678,00

The cell-permeant mag-fluo-4, AM is an analog of fluo-4 with a K_d for Mg²⁺ of 4.7 mM and a Kd for Ca²⁺ of 22 μM, making it useful as an intracellular Mg²⁺ indicator as well as a low-affinity Ca²⁺ indicator.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Detection MethodFluorescence

Dye TypeMag-Fluo-4

Emission Wavelength517 nm

Excitation Wavelength493 nm

Quantity10 x 50 μg

Shipping ConditionRoom Temperature

For Use With (Application)Magnesium Indicator

For Use With (Equipment)Fluorescence Microscope, Flow Cytometer

Product TypeMag-Fluo-4 AM

Unit SizeEach

Contents & Storage

Store in freezer -5°C to -30°C and protect from light.

Citations & References (24)

Citations & References

Abstract

Mitochondrial modulation of Ca2+ -induced Ca2+ -release in rat sensory neurons.

Authors:Jackson JG, Thayer SA

Journal:J Neurophysiol

PubMed ID:16760347

'Ca2+ -induced Ca2+ -release (CICR) from ryanodine-sensitive Ca2+ stores provides a mechanism to amplify and propagate a transient increase in intracellular calcium concentration ([Ca2+]i). A subset of rat dorsal root ganglion neurons in culture exhibited regenerative CICR when sensitized by caffeine. [Ca2+]i oscillated in the maintained presence of 5 mM ... More

Rapid functional assays of recombinant IP3 receptors.

Authors:Laude AJ, Tovey SC, Dedos SG, Potter BV, Lummis SC, Taylor CW

Journal:Cell Calcium

PubMed ID:15963563

'Functional assays of inositol 1,4,5-trisphosphate receptors (IP3R) currently use 45Ca2+ release methods, fluorescent Ca2+ indicators within either the ER or cytosol, or electrophysiological analyses of IP3R in the nuclear envelope or artificial bilayers. None of the methods is presently amenable to the rapid, high-throughput quantitative analyses of IP3R function needed ... More

The endoplasmic reticulum: one continuous or several separate Ca(2+) stores?

Authors:Petersen OH, Tepikin A, Park MK

Journal:Trends Neurosci

PubMed ID:11311379

The Ca2+ store and sink in the endoplasmic reticulum (ER) is important for Ca2+ signal integration and for conveyance of information in spatial and temporal domains. Textbooks regard the ER as one continuous network, but biochemical and biophysical studies revealed apparently discrete ER Ca2+ stores. Recent direct studies of ER ... More

Real-time observations of intracellular Mg2+ signaling and waves in a single living ventricular myocyte cell.

Authors:Lee S, Lee HG, Kang SH,

Journal:Anal Chem

PubMed ID:19086893

Despite the important regulatory role of Mg(2+) in metabolic pathways, its underlying mechanism is not completely understood at the single-cell level. This study examined the propagation and dynamics of Mg(2+) signaling across the cell membrane by employing the real-time visualization of intracellular Mg(2+) waves in living ventricular myocytes using a ... More

TRPC channels determine human keratinocyte differentiation: new insight into basal cell carcinoma.

Authors:Beck B, Lehen'kyi V, Roudbaraki M, Flourakis M, Charveron M, Bordat P, Polakowska R, Prevarskaya N, Skryma R,

Journal:Cell Calcium

PubMed ID:17920677

Aberrant keratinocyte differentiation is considered to be a key mechanism in the onset of hyperproliferative dermatological diseases, including basal cell carcinoma (BCC). It is, therefore, vital to understand what drives keratinocytes to develop such pathological phenotypes. The role of calcium in keratinocyte differentiation is uncontested but the mechanisms controlling calcium-induced ... More

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