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D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals
Référence: A11446.06
5 g, Each
Thermo Scientific Chemicals
D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals
Référence: A11446.06
5 g, Each
Quantité
Référence: A11446.06
également connu sous le numéro A11446-06
Prix (EUR)
62,73 Prix en ligne
69,70
Each
Quantité
-
Identifiants chimiques
CAS
52-67-5
IUPAC Name
(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
Molecular Formula
C5H11NO2S
InChI Key
VVNCNSJFMMFHPL-VKHMYHEASA-N
SMILES
CC(C)(S)[C@@H](N)C(O)=O
Spécifications
Fiche de spécificationsForm
Powder
Assay (Non-aqueous acid-base Titration)
≥97.5 to ≤102.5%
Appearance (Color)
White to pale cream
Optical Rotation
-62.5? ? 2? (c=5%, 1N NaOH)
Description
It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages, by reducing the activity of Interleukin 1 and rheumatoid factor and in preventing crosslinking of the collagen. It acts as an exogenous NOS modulator.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
It is freely soluble in water, slightly soluble in alcohol, insoluble in chloroform, ether, acetone, benzene, and in carbon tetrachloride.
Notes
Stable under normal conditions. Incompatabile to strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C.
It is freely soluble in water, slightly soluble in alcohol, insoluble in chloroform, ether, acetone, benzene, and in carbon tetrachloride.
Notes
Stable under normal conditions. Incompatabile to strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C.
RUO – Research Use Only
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Sécurité et manipulation
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Respiratory Sensitization
Category 1
Reproductive Toxicity
Category 1B
Label Elements
Signal Word
Danger
Hazard Statements
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360D - May damage the unborn child
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P284 - Wear respiratory protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P308 + P313 - IF exposed or concerned: Get medical advice/attention
P332 + P313 - If skin irritation occurs: Get medical advice/attention
P342 + P311 - If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician
Additional EU labelling
Restricted to professional users