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Citations et références (12)
Invitrogen™
Azide de biotine (PEG4 carboxamide-6-Azidohexanyl Biotine)
L’haptène, de l’azoture de biotine, est réactif avec des alcynes terminaux par le biais d’une réaction clic catalysée par duAfficher plus
| Référence | Quantité |
|---|---|
| B10184 | 1 mg |
Référence B10184
Prix (EUR)
514,00
Each
Quantité:
1 mg
Prix (EUR)
514,00
Each
L’haptène, de l’azoture de biotine, est réactif avec des alcynes terminaux par le biais d’une réaction clic catalysée par du cuivre. La biotine peut ensuite être détectée avec de la streptavidine, de l’avidine ou la protéine de liaison à la biotine NeutrAvidin®.
Usage exclusivement réservé à la recherche. Ne pas utiliser pour des procédures de diagnostic.
Spécifications
Réactivité chimiqueAlcyne
FormatSolide
Marqueur ou colorantBiotine
Poids moléculaire615,79 Da
Type de produitAzide de biotine
Quantité1 mg
Groupe de réactifsAzoture
Groupement de réactifsAmine, azoture
Conditions d’expéditionTempérature ambiante
SolubilitéDMSO (diméthylsulfoxyde)
CouleurBiotine
Type d’étiquetteBiotine et autres haptènes
Gamme de produitsMolecular Probes
Unit SizeEach
Contenu et stockage
Stocker à ≤-20°C et desséché.
Citations et références (12)
Citations et références
Abstract
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.
Journal:Proc Natl Acad Sci U S A
PubMed ID:20018730
'To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5'' to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) controls the supercoiling of DNA by nicking, rotating, and religating one strand of DNA.
Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.
Journal:Chem Res Toxicol
PubMed ID:18232660
'Polyunsaturated fatty acids (PUFA) are primary targets of free radical damage during oxidative stress. Diffusible electrophilic alpha,beta-unsaturated aldehydes, such as 4-hydroxynonenal (HNE), have been shown to modify proteins that mediate cell signaling (e.g., IKK and Keap1) and alter gene expression pathways responsible for inducing antioxidant genes, heat shock proteins, and
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.
Journal:
PubMed ID:24589582
'Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway in a tumor-prone mouse model (Mcm4(chaos3)) with a
Metabolic labeling of sialic acids in living animals with alkynyl sugars.
Journal:Angew Chem Int Ed Engl
PubMed ID:19388017
Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living
Regulation of the Skeletal Muscle Ryanodine Receptor/Ca2+-release Channel RyR1 by S-Palmitoylation.
Journal:
PubMed ID:24509862
The ryanodine receptor/Ca(2+)-release channels (RyRs) of skeletal and cardiac muscle are essential for Ca(2+) release from the sarcoplasmic reticulum that mediates excitation-contraction coupling. It has been shown that RyR activity is regulated by dynamic post-translational modifications of Cys residues, in particular S-nitrosylation and S-oxidation. Here we show that the predominant