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Thermo Scientific™
TheraPure™ S-Adenosyl-L-Methionine (32 mM)
S-Adenosyl-L-Methionine (SAM) serves as a high-purity methyl donor for both Cap-0 and Cap-1 formation, ensuring efficient and reliable enzymatic capping processes. With its high purity and stability, SAM helps maintain optimal reaction conditions, leading to consistent and high-quality mRNA production.
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| Référence | Quantité |
|---|---|
| B3422TPB014 | 1 ml |
| B3422TPB002 | 2 ml |
| B3422TPB008 | 6 ml |
| B3422TPB003 | 15 ml |
Référence B3422TPB014
Prix (EUR)
-
Quantité:
1 ml
Thermo Scientific TheraPure products for post-transcriptional capping are intended for use in the synthesis of mRNA in the development of mRNA therapeutics and vaccines.
Post-transcriptional capping involves adding a 5' cap structure to mRNA after transcription, enhancing mRNA stability and translation efficiency. The process uses TheraPure Vaccinia Capping Enzyme and TheraPure 2'-O-Methyltransferase for adding the cap structures and TheraPure S-Adenosyl-L-Methionine as a methyl donor. Capping efficiency can reach >95%.
Designed for process development
TheraPure Vaccinia Capping Enzyme is a highly efficient enzyme used for adding 7-methylguanylate cap structures (Cap-0) to the 5' ends of uncapped RNA. This capping is essential for the stability and translational efficiency of mRNA.
TheraPure 2'-O-Methyltransferase is a high-purity enzyme designed for the methylation of RNA molecules, specifically adding a methyl group to the 2'-O position of the ribose sugar (Cap-1).
TheraPure S-Adenosyl-L-Methionine is a high-purity reagent used as a methyl group donor in post-transcriptional capping for Cap-0 and Cap-1 structure.
These TheraPure products are essential tools in the field of molecular biology, providing researchers with reliable and high-quality enzymes and reagents to advance the development of mRNA therapeutics and vaccines.
For Research Use Only.
Spécifications
Tampon compatible10X Capping buffer
Type de produitMethyl Donor
Quantité1 ml
Conditions d’expédition-25°C to -15°C
Concentration32 mM
EnzymesS-Adenosyl-L-Methionine
FormeLiquid
Catégorie de rechercheDrug Development
Sensible à l’inactivation thermiqueNo
Unit SizeEach