5’-O-(tertiobutyldiméthylsilyl) thymidine, +97 %, Thermo Scientific Chemicals

Référence	Quantité
H52301.03 également connu sous le numéro H52301-03	1 g

Référence H52301.03

également connu sous le numéro H52301-03

Prix (EUR)

111,00

Quantité:

Grand volume ou format personnalisé

Prix (EUR)

111,00

Identifiants chimiques

CAS40733-28-6

IUPAC Name1-[(2R,4S,5R)-5-{[(tert-butyldimethylsilyl)oxy]methyl}-4-hydroxyoxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Molecular FormulaC16H28N2O5Si

InChI KeyIJWIJLIIOKZJMS-YNEHKIRRSA-N

SMILESCC1=CN([C@H]2C[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)C(=O)NC1=O

Spécifications Specification Sheet

FormPowder

Assay from Supplier's CofA≥97.0%

CommentIdentification by NMR: Conforms

Appearance (Color)White to off-white

Loss on Drying≤1.0%

5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
La 5′-O-(tert-butyldiméthylsilyl)thymidine est utilisée comme intermédiaire pharmaceutique.

Remarques
Stable dans les conditions de stockage recommandées. Incompatible avec les agents oxydants.

RUO – Research Use Only

Références générales :

Masayoshi Takase ; Masahiko Inouye. Highly efficient recognition of native TpT by artificial ditopic hydrogen-bonding receptors possessing a conformationally well-defined linkage. J. Org. Chem. 2003, 68, (3),1134-1137
Yixin Lu. Recent advances in the stereocontrolled synthesis of antisense phosphorothioates. Mini Reviews in Medicinal Chemistry. 2006, 6, (3),319-330