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Thermo Scientific Chemicals

Everolimus, Thermo Scientific Chemicals

Référence: J60139.LB0
5 mg, Each
Everolimus, Thermo Scientific Chemicals
Everolimus, Thermo Scientific Chemicals
Everolimus, Thermo Scientific Chemicals
Certificats
Thermo Scientific Chemicals

Everolimus, Thermo Scientific Chemicals

Référence: J60139.LB0
5 mg, Each
Quantité
Certificats
Informational:Informatif:Il est possible que nous ayons besoin d’informations supplémentaires concernant ce produit chimique pour nos rapports de conformité réglementaire et chimique. Nous vous contacterons pour obtenir ces informations une fois votre commande passée, si nécessaire.
Référence: J60139.LB0
également connu sous le numéro J60139-#0
Prix (EUR)
135,00 Prix en ligne
150,00
Each
Quantité
-
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Identifiants chimiques

CAS
159351-69-6
IUPAC Name
(1R,9S,12S,15R,16Z,18R,19R,21R,23S,24E,26Z,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular Formula
C53H83NO14
InChI Key
HKVAMNSJSFKALM-CNPAPGRKSA-N
SMILES
CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)C=C(C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=C/C=C(C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OCCO

Spécifications

Fiche de spécificationsFiche de spécifications
Form
Powder or crystals or crystalline powder or granules or amorphous solid
Appearance (Color)
White to off-white to pale yellow
Assay from Suppliers CofA
≥95.0%

Description

Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

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    Sécurité et manipulation


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Specific target organ toxicity - (repeated exposure)
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H372 - Causes damage to organs through prolonged or repeated exposure

    Precautionary Statements

    P260 - Do not breathe dust/fume/gas/mist/vapors/spray

    P314 - Get medical advice/attention if you feel unwell