A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca
2+ ions. It is also used in white wine production.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubilité
Soluble dans l’eau, le diméthylformamide, l’éthanol, la solution saline tamponnée au phosphate, l’alcool dilué, l’ammoniac liquide et le diméthylsulfoxyde.
Remarques
Stockez-le dans un endroit frais. Incompatible avec les agents oxydants forts.
RUO – Research Use Only
Références générales :
- Deheshi, S. ; Dabiri, B. ; Fan, S. ; Tsang, M. ; Rintoul, G. L. Les changements dans la morphologie mitochondriale induits par le calcium ou la roténone dans les astrocytes primaires se produisent principalement par le biais du remodelage médié par les ROS. J. Neurochem. 2015, 133 (5), 684-699.
- Li, X. ; Zheng, L. ; Wang, Y. ; Zhang, N. ; Lou-__LW_AT__, Y ; Xiao, T.; Liu, J. Un nouvel électrocatalyseur à haute sensibilité pour détecter le glutathion réduit par 2-hydroxypropyl- β cyclodextrine enveloppé dans du 10-méthylphénothiazine. RSC Adv. 2015, 5 (88), 71749-71755.