A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease. For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Spécifications
Conjugué
Tb (Terbium)/Lanthanide Chelates
Quantité
25 μg
Excitation / émission
340⁄490, 520
Réactivité
Human
Conditions d’expédition
Dry Ice
Affichage
End Point
Abrv de la réactivité
Hu
Gène cible
Ser/Thr Kinases
Gamme de produits
LanthaScreen™
Contenu et stockage
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.
Figures
Documentation et téléchargements
Certificats
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