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Invitrogen
CCAR1 Polyclonal Antibody
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FIGURE: 1 / 4
CCAR1 Antibody (PA5-92909) in WB
Western blot analysis of CCAR1 in extracts of Mouse testis. Samples were incubated with CCAR1 Polyclonal antibody (Product # PA5-92909) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 5s.
Product Details
PA5-92909
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CCAR1 (NP_0607072)
Conjugate
Form
Liquid
Concentration
1.61 mg/mL
Amount
161 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAQFGGQKNP PWATQFTATA VSQPAALGVQ QPSLLGASPT IYTQQTALAA AGLTTQTPAN YQLTQTAALQ QQAAAAAAAL QQQYSQPQQA LYSVQQQLQQ PQQTLLTQPA VALPTSLSLS TPQPTAQITV SYPTPRSSQQ QTQPQKQRVF TGVVTKLHDT FGFVDEDVFF QLSAVKGKTP QVGDRVLVEA TYNPNMPFKW; Positive Samples: HeLa, Jurkat, HepG2, A-549, U-251MG, A-431; Cellular Location: Cytoplasm, perinuclear region
Target Information
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-betas, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CARP-1; CARP1; Cell cycle and apoptosis regulatory protein 1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; MGC44628; OTTHUMP00000019709; RP11-437A18.1; unnamed protein product
Gene Aliases: 2610511G16Rik; 9430036H15Rik; CARP1; CCAR1; DIS; RGD1560358; uc.285+
UniProt ID: (Human) Q8IX12, (Mouse) Q8CH18
Entrez Gene ID: (Human) 55749, (Rat) 361849, (Mouse) 67500
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
RNA binding
protein binding
ubiquitin protein ligase activity
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
chromatin/chromatin-binding, or -regulatory protein
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
apoptotic process
positive regulation of cell proliferation
protein ubiquitination
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
cell division
transcription, DNA-templated
cell cycle
regulation of nucleic acid-templated transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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