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Abnova
HOXD3 Monoclonal Antibody (3C2)
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Product Details
H00003232-M10
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3C2
Immunogen
HOXD3 (NP_008829, 334 a.a. approximately 431 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: FEPHPMASNG GGFASANLQG SPVYVGGNFV ESMAPASGPV FNLGHLSHPS SASVDYSCAA QIPGNHHHGP CDPHPTYTDL SAHHSSQGRL PEAPKLTH
Target Information
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box D3; Homeobox protein Hox-4A; Homeobox protein Hox-D3; Hox-4.1, mouse, homolog of; MGC10470
Gene Aliases: Hox-4.1; HOX1D; HOX4; HOX4A; HOXD3
UniProt ID: (Human) P31249
Entrez Gene ID: (Human) 3232
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell-matrix adhesion
Notch signaling pathway
anterior/posterior pattern specification
positive regulation of gene expression
glossopharyngeal nerve morphogenesis
thyroid gland development
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
cartilage development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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