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인용 및 참조 문헌 (3)
Thermo Scientific™
Sulfo-EMCS (N-ε-maleimidocaproyl-oxysulfosuccinimide ester)
Thermo Scientific Pierce Sulfo-EMCS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| 22307 | 50 mg |
카탈로그 번호 22307
제품 가격(KRW)
485,000
Online offer
Ends: 31-Dec-2025
570,000할인액 85,000 (15%)
Each
수량:
50 mg
제품 가격(KRW)
485,000
Online offer
Ends: 31-Dec-2025
570,000할인액 85,000 (15%)
Each
Thermo Scientific Pierce Sulfo-EMCS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).
Features of Sulfo-EMCS:
• Reactive groups: sulfo-NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Sulfo-NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-soluble (compare to EMCS)
• Aliphatic spacer offers low potential for eliciting an immune response
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
EMCS (N-ε-malemidocaproyl-oxysuccinimide ester)
Features of Sulfo-EMCS:
• Reactive groups: sulfo-NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Sulfo-NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-soluble (compare to EMCS)
• Aliphatic spacer offers low potential for eliciting an immune response
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
EMCS (N-ε-malemidocaproyl-oxysuccinimide ester)
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성No
설명Sulfo-EMCS
형태Powder
라벨링 방법Chemical Labeling
분자량410.33
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, Sulfo-NHS Ester
배송 조건Ambient
용해도Water
스페이서 암 길이9.4 Å
수용성Yes
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Short (<10 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for Sulfo-EMCS (N-ε-maleimidocaproyl-oxysulfosuccinimide ester)?
인용 및 참조 문헌 (3)
인용 및 참조 문헌
Abstract
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
Journal:J Biol Chem
PubMed ID:16847063
'A comprehensive, unbiased inventory of synuclein forms present in Lewy bodies from patients with dementia with Lewy bodies was carried out using two-dimensional immunoblot analysis, novel sandwich enzyme-linked immunosorbent assays with modification-specific synuclein antibodies, and mass spectroscopy. The predominant modification of alpha-synuclein in Lewy bodies is a single phosphorylation at
An on-chip thin film photodetector for the quantification of DNA probes and targets in microarrays.
Journal:Nucleic Acids Res
PubMed ID:15148343
A flat microdevice which incorporates a thin-film amorphous silicon (a-Si:H) photodetector with an upper layer of functionalized SiO2 is used to quantify the density of both immobilized and hybridized DNA oligonucleotides labeled with a fluorophore. The device is based on the photoconductivity of hydrogenated amorphous silicon in a coplanar electrode
Functionalization of poly(methyl methacrylate) (PMMA) as a substrate for DNA microarrays.
Journal:Nucleic Acids Res
PubMed ID:14718554
A chemical procedure was developed to functionalize poly(methyl methacrylate) (PMMA) substrates. PMMA is reacted with hexamethylene diamine to yield an aminated surface for immobilizing DNA in microarrays. The density of primary NH2 groups was 0.29 nmol/cm2. The availability of these primary amines was confirmed by the immobilization of DNA probes