Thermo Scientific Pierce Sulfo-SMPB is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of자세히 알아보기
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카탈로그 번호
수량
22317
50 mg
카탈로그 번호 22317
제품 가격(KRW)
352,000
Online offer
Ends: 31-Mar-2026
628,000
할인액 276,000 (44%)
Each
카트에 추가하기
수량:
50 mg
대량 주문 또는 맞춤형 요청
제품 가격(KRW)
352,000
Online offer
Ends: 31-Mar-2026
628,000
할인액 276,000 (44%)
Each
카트에 추가하기
Thermo Scientific Pierce Sulfo-SMPB is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).
Features of Sulfo-SMPB:
• Reactive groups: sulfo-NHS ester and maleimide • Reactive towards: amino and sulfhydryl groups • Extended chain length limits steric hindrance • Non-cleavable • Water-soluble (compare to SMPB) • Membrane impermeable, allowing for cell surface labeling
Product References: Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성No
설명Sulfo-SMPB
형태Powder
라벨링 방법Chemical Labeling
분자량458.37
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide, Sulfo-NHS Ester
배송 조건Ambient
용해도Water
스페이서 암 길이11.6 Å
수용성Yes
화학물질 반응성Amine-Sulfhydryl
CleavableNo
교차결합제 유형Heterobifunctional
형식Standard
제품 유형Crosslinker
스페이서Medium (10 to 30 Å)
Unit SizeEach
구성 및 보관
Upon receipt store desiccated at -20°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)?
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.
pICln inhibits snRNP biogenesis by binding core spliceosomal proteins.
Authors:Pu WT, Krapivinsky GB, Krapivinsky L, Clapham DE
Journal:Mol Cell Biol
PubMed ID:10330151
'The U1, U2, U4, U5, and U6 small nuclear ribonucleoproteins (snRNPs) form essential components of spliceosomes, the machinery that removes introns from pre-mRNAs in eukaryotic cells. A critical initial step in the complex process of snRNP biogenesis is the assembly of a group of common core proteins (Sm proteins) on ... More
Substrate-induced conformational change in bacterial complex I.
Authors:Mamedova AA, Holt PJ, Carroll J, Sazanov LA
Journal:J Biol Chem
PubMed ID:15037611
'The mechanism coupling electron transfer and proton pumping in respiratory complex I (NADH-ubiquinone oxidoreductase) has not been established, but it has been suggested that it involves conformational changes. Here, the influence of substrates on the conformation of purified complex I from Escherichia coli was studied by cross-linking and electron microscopy. ... More
Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
Decorin inhibits the epidermal growth factor receptor (EGFR) by down-regulating its tyrosine kinase activity, thereby blocking the growth of a variety of transformed cells and tumor xenografts. In this study we provide evidence that decorin directly binds to the EGFR causing its dimerization, internalization, and ultimately its degradation. Using various ... More
Combination of DNA-directed immobilization and immuno-PCR: very sensitive antigen detection by means of self-assembled DNA-protein conjugates.
Authors:Niemeyer CM, Wacker R, Adler M
Journal:Nucleic Acids Res
PubMed ID:12907742
An assay for very sensitive antigen detection is described which takes advantage of the self- assembly capabilities of semi-synthetic conjugates of DNA and proteins. The general scheme of this assay is similar to a two-sided (sandwich) enzyme-linked immunoassay (ELISA); however, covalent single-stranded DNA-streptavidin (STV) conjugates, capable of hybridizing to complementary ... More
Biologically active decorin is a monomer in solution.
It has been reported that decorin and its protein core can have molecular masses nearly double the size of those previously published, suggesting a dimeric structure. In this study we tested whether biologically active decorin and its glycoprotein core would form dimers in solution. We used homo- and hetero-bifunctional chemical ... More