KaryoStat™ Assay

The KaryoStat Assay is an alternative to g-banding karyotyping offering accurate genotyping (sample ID) plus whole-genome coverage for accurate detection of chromosomal abnormalities with results in 2.5 days. The assay enables the detection of aneuploidies, submicroscopic aberrations, and mosaic events for research use. Because the assay provides genotype information, it can help in the identification of triploidies and copy neutral events such as absence of heterozygosity. Our proprietary manufacturing technology produces arrays that are highly reproducible between each batch with no risk of probe dropout inherent in bead manufacturing techniques. The assay includes arrays, reagents, and easy-to-use data analysis software for a cost-effective and streamlined analysis of pluripotent stem cell lines.

Features include:
• Cost effective and accurate detection of chromosomal abnormalities
• Karyotyping and genotyping (sample ID) with one assay
• Simple analysis; no cytogenetics expertise necessary
• Assay includes arrays, reagents, and free downloadable software
• 2.5 days to results

	KaryoStat Assay	KaryoStat HD Assay
Gains	>2 Mb	>25–50 kb
Losses	>1 Mb	>25–50 kb
Absence of heterozygosity	>5 Mb	>1 Mb
SNP	Yes	Yes
Coverage	Low	Highest
Instrument	GeneChip Scanner 3000 only	GeneChip Scanner 3000 only
Analysis software	Chromosomal Analysis Suite	Chromosomal Analysis Suite