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NHLH2 Monoclonal Antibody (3E11)
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Product Details
H00004808-M03
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3E11
Immunogen
NHLH2 (NP_005590, 36 a.a. approximately 135 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: SDLEPVEEAE GDGKGGSRAA LYPHPQQLSR EEKRRRRRAT AKYRSAHATR ERIRVEAFN LAFAELRKLL PTLPPDKKLS KIEILRLAIC YISYLNHVLD V
Target Information
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHa34; Class A basic helix-loop-helix protein 34; Helix-loop-helix protein 2; HEN-2; Nescient helix loop helix 2; NSCL-2; unnamed protein product
Gene Aliases: BHLHA34; HEN2; HH27; KIAA0490; NHLH2; NSCL2
UniProt ID: (Human) Q02577
Entrez Gene ID: (Human) 4808
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription coactivator binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
protein dimerization activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
regulation of transcription from RNA polymerase II promoter
apoptotic process
central nervous system development
peripheral nervous system development
male gonad development
cell migration in hindbrain
hypothalamus gonadotrophin-releasing hormone neuron development
cell differentiation
ovulation cycle
positive regulation of transcription from RNA polymerase II promoter
male mating behavior
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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