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          • Primary Antibodies ›
          • Ferritin Heavy Chain Antibodies

          Invitrogen

          Ferritin Heavy Chain Recombinant Rabbit Monoclonal Antibody (23GB1860)

          Advanced Verification
          View all (28) Ferritin Heavy Chain antibodies

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          Cite Ferritin Heavy Chain Recombinant Rabbit Monoclonal Antibody (23GB1860)

          Additional Information:
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          • Antibody Testing Data (2)
          • Advanced Verification (1)
          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Ferritin Heavy Chain Antibody (MA5-53996) in ICC/IF

          Immunocytochemistry analysis of Ferritin Heavy Chain in HepG2 cells. Nuclei were stained blue with DAPI; Ferritin Heavy Chain recombinant monoclonal antibody (Product # MA5-53996) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar: 20 μm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody
          Ferritin Heavy Chain Recombinant Rabbit Monoclonal Antibody (23GB1860)

          Product Details

          MA5-53996

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:2,500
          -

          Immunocytochemistry (ICC/IF)

          1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          23GB1860

          Immunogen

          A synthesized peptide derived from human Ferritin Heavy Chain (150-183AA).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3248467

          Target Information

          FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; ferritin heavy subunit; ferritin, heavy polypeptide 1; frih; H-ferritin; iron-binding; immunosuppressor; growth factor; MGC104426; PIG15; placenta immunoregulatory factor; proliferation-inducing protein 15; unnamed protein product

          View more View less

          Gene Aliases: FHC; FTH; FTH1; FTHL6; HFE5; NBIA9; OK/SW-cl.84; PIG15; PLIF

          View more View less

          UniProt ID: (Human) P02794

          View more View less

          Entrez Gene ID: (Human) 2495

          View more View less

          Function(s)
          ferroxidase activity iron ion binding protein binding ferrous iron binding ferric iron binding oxidoreductase activity identical protein binding metal ion binding iron ion sequestering activity
          Process(es)
          iron ion transport cellular iron ion homeostasis immune response negative regulation of cell proliferation negative regulation of fibroblast proliferation negative regulation of ferroptosis
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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