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Actin Polyclonal Antibody
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Product Details
OSA00076W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Sheep
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the c-terminal of human beta, gamma, kappa Actin (ACTB, ACTG, ACTK) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in many species including rat, mouse, zebra fish and xenopus.
Specificity of this antibody: Actin.
Target Information
The function of this target is Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Subunit: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Subcellular Location: Cytoplasm, cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Actin is a protein with a high degree of evolutionary conservation that undergoes polymerization to generate filaments, which subsequently assemble into interconnected networks within the cytoplasm of cells.; Actin, cytoplasmic 1; Actin, cytoplasmic 2; actin, gamma, cytoplasmic 1; beta cytoskeletal actin; Beta-actin; beta-actin FE-3; cytoplasmic beta-actin; cytoskeletal gamma-actin; epididymis luminal protein 176; Gamma-actin; I(2)-actin; PS1TP5-binding protein 1; unnamed protein product
Gene Aliases: ACT; ACTB; ACTG; ACTG1; Actl; Actx; AL023024; beta-actin; BKRNS; BNS; BRWS1; CSMH; DDS1; DFNA20; DFNA26; E430023M04Rik; E51; HEL-176; PS1TP5BP1; THC8
UniProt ID: (Human) P60709, (Human) P63261, (Rat) P60711, (Mouse) P60710, (Mouse) P63260, (Rat) P63259
Entrez Gene ID: (Human) 60, (Human) 71, (Rat) 81822, (Mouse) 11461, (Mouse) 11465, (Rat) 287876
nucleotide binding
structural constituent of cytoskeleton
protein binding
ATP binding
hydrolase activity
ATPase activity
kinesin binding
protein kinase binding
nitric-oxide synthase regulator activity
Tat protein binding
nucleosomal DNA binding
identical protein binding
tau protein binding
nitric-oxide synthase binding
structural constituent of postsynaptic actin cytoskeleton
transporter regulator activity
profilin binding
ubiquitin protein ligase binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
molecular_function
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
morphogenesis of a polarized epithelium
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
cytoskeleton organization
establishment or maintenance of cell polarity
axonogenesis
positive regulation of cell proliferation
substantia nigra development
regulation of mitotic metaphase/anaphase transition
adherens junction assembly
maintenance of blood-brain barrier
regulation of apoptotic process
apical protein localization
positive regulation of T cell differentiation
negative regulation of cell differentiation
positive regulation of cell differentiation
positive regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
cell motility
regulation of norepinephrine uptake
positive regulation of norepinephrine uptake
regulation of cell cycle
regulation of G0 to G1 transition
platelet aggregation
protein localization to adherens junction
cellular response to cytochalasin B
postsynaptic actin cytoskeleton organization
regulation of transepithelial transport
regulation of synaptic vesicle endocytosis
positive regulation of stem cell population maintenance
regulation of protein localization to plasma membrane
positive regulation of double-strand break repair via homologous recombination
regulation of G1/S transition of mitotic cell cycle
regulation of double-strand break repair
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
angiogenesis
positive regulation of gene expression
positive regulation of cell migration
sarcomere organization
regulation of stress fiber assembly
regulation of focal adhesion assembly
cellular response to interferon-gamma
positive regulation of wound healing
tight junction assembly
protein localization to bicellular tight junction
retina homeostasis
ATP-dependent chromatin remodeling
retina development in camera-type eye
cellular response to electrical stimulus
response to calcium ion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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