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Bethyl Laboratories
SNRNP200 Polyclonal Antibody
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FIGURE: 1 / 4
SNRNP200 Antibody (A303-454A-T) in IHC (P)
Detection of human SNRNP200 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- SNRNP200 (Product # A303-454A) (Lot 2) used at a dilution of 1:5,000 (0.2 µg/mL). Detection: DAB. Counterstain: hematoxylin (blue).
Product Details
A303-454A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 400 and 450 of Human Small Nuclear Ribonucleoprotein 200kDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating signal cointegrator 1 complex subunit 3-like 1; bad response to refrigeration 2 homolog; BRR2 homolog; contains two DEXH helicase domains; hBRR2/200K protein; U5-200K; small nuclear ribonucleoprotein 200kDa (U5); small nuclear ribonucleoprotein, U5 200kDa subunit; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family); U5-200KD; unnamed protein product
Gene Aliases: A330064G03Rik; ASCC3L1; BC011390; BRR2; HELIC2; KIAA0788; RP33; SNRNP200; U5-200-KD; U5-200KD
UniProt ID: (Human) O75643, (Mouse) Q6P4T2
Entrez Gene ID: (Human) 23020, (Mouse) 320632
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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