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Invitrogen
WNT5B Recombinant Rabbit Monoclonal Antibody (24GB2690)
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FIGURE: 1 / 3
WNT5B Antibody (MA5-57322) in ICC/IF
Immunocytochemical staining of WNT5B in HepG2 cells using WNT5B Recombinant Monoclonal Antibody (Product # MA5-57321) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Wnt family member 5B was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 μm.
Product Details
MA5-57322
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB2690
Immunogen
A synthesized peptide derived from human Wnt5b (aa 300-359)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
20 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-5b; unnamed protein product; wingless-related MMTV integration site 5B; wingless-type MMTV integration site family, member 5B; WNT-5B protein
Gene Aliases: AW545702; Wnt-5b; WNT5B
UniProt ID: (Human) Q9H1J7, (Mouse) P22726
Entrez Gene ID: (Human) 81029, (Rat) 282582, (Mouse) 22419
chondrocyte differentiation
Wnt signaling pathway
neuron differentiation
positive regulation of cell migration
muscle cell differentiation
cell fate commitment
fat cell differentiation
positive regulation of fat cell differentiation
canonical Wnt signaling pathway
lens fiber cell development
cellular response to retinoic acid
negative regulation of canonical Wnt signaling pathway
positive regulation of convergent extension involved in gastrulation
positive regulation of non-canonical Wnt signaling pathway
wound healing
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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