EGTA, Tetra(acetoxymethyl Ester) (EGTA, AM)

El EGTA, AM que penetra en las células puede cargar de forma pasiva en las células para generar EGTA intracelular.Más información

Número de catálogo	Cantidad
E1219	10 mg

Número de catálogo E1219

Precio (MXN)

Cantidad:

10 mg

El EGTA, AM que penetra en las células puede cargar de forma pasiva en las células para generar EGTA intracelular. Este compuesto es intrínsecamente un líquido o un aceite a temperatura ambiente.

Obtenga más información sobre los indicadores de iones, incluidos los indicadores de calcio, potasio, pH y potencial de la membrana ›

Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.

Especificaciones

Tipo de coloranteQuelante (no fluorescente)

Cantidad10 mg

Condiciones de envíoTemperatura ambiente

Tipo de productoAM EGTA

Unit SizeEach

Contenido y almacenamiento

Almacenar en congelador entre -5 °C y -30 °C

Citations & References (93)

Citations & References

Abstract

Alpha-adducin dissociates from F-actin and spectrin during platelet activation.

Authors:Barkalow KL, Italiano JE, Chou DE, Matsuoka Y, Bennett V, Hartwig JH

Journal:J Cell Biol

PubMed ID:12743105

'Aspectrin-based skeleton uniformly underlies and supports the plasma membrane of the resting platelet, but remodels and centralizes in the activated platelet. alpha-Adducin, a phosphoprotein that forms a ternary complex with F-actin and spectrin, is dephosphorylated and mostly bound to spectrin in the membrane skeleton of the resting platelet at sites ... More

The platelet cytoskeleton regulates the affinity of the integrin alpha(IIb)beta(3) for fibrinogen.

Authors:Bennett JS, Zigmond S, Vilaire G, Cunningham ME, Bednar B

Journal:J Biol Chem

PubMed ID:10464255

'Agonist-generated inside-out signals enable the platelet integrin alpha(IIb)beta(3) to bind soluble ligands such as fibrinogen. We found that inhibiting actin polymerization in unstimulated platelets with cytochalasin D or latrunculin A mimics the effects of platelet agonists by inducing fibrinogen binding to alpha(IIb)beta(3). By contrast, stabilizing actin filaments with jasplakinolide prevented ... More

Feedback inhibition of sodium/calcium exchange by mitochondrial calcium accumulation.

Authors:Opuni K, Reeves JP

Journal:J Biol Chem

PubMed ID:10801871

'Chinese hamster ovary cells expressing the bovine cardiac Na(+)/Ca(2+) exchanger were subjected to two periods of 5 and 3 min, respectively, during which the extracellular Na(+) concentration ([Na(+)](o)) was reduced to 20 mm; these intervals were separated by a 5-min recovery period at 140 mm Na(+)(o). The cytosolic Ca(2+) concentration ... More

Early cellular events couple covalent binding of reactive metabolites to cell killing by nephrotoxic cysteine conjugates.

Authors:Chen Q, Jones TW, Stevens JL

Journal:J Cell Physiol

PubMed ID:7525611

'Addition of the nephrotoxic cysteine conjugate, S-(1,2-dichlorovinyl)-L-cysteine (DCVC), to the LLC-PK1 line of renal epithelial cells leads to covalent binding of reactive intermediates followed by thiol depletion, lipid peroxidation, and cell death (Chen et al., 1990, J. Biol. Chem., 265:21603-21611). The present study was designed to determine if increased intracellular ... More

Cell type-specific modes of feedback regulation of capacitative calcium entry.

Authors:Louzao MC, Ribeiro CM, Bird GS, Putney JW

Journal:J Biol Chem

PubMed ID:8662975

'The Ca2+-ATPase inhibitor, thapsigargin, activated Ca2+ entry into pancreatic acinar cells, a process known as capacitative calcium entry. In cells loaded with the calcium chelator BAPTA, the transient Ca2+ release was blunted and the rise of [Ca2+]i on readdition of Ca2+ was slowed. However, the steady-state [Ca2+]i due to Ca2+ ... More

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