Search
Invitrogen
Hemoglobin Monoclonal Antibody (HB11-231.2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
Hemoglobin Antibody (MA5-46037) in ICC/IF
Immunofluorescence analysis of Hemoglobin was performed using K-562 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Hemoglobin Monoclonal Antibody (HB11-231.2) (Product # MA1-10808) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius over... View More
Product Details
MA5-46037
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
HB11-231.2
Immunogen
Purified human hemoglobin.
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-10808 detects Hemoglobin from human samples. This antibody does not detect bovine, chicken, equine, ovine, or porcine Hemoglobin.
MA1-10808 has been successfully used in ELISA and Western blot applications.
The MA1-10808 immunogen is purified human hemoglobin.
Target Information
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: alpha globin chain; alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; beta globin; beta globin chain; Beta-globin; delta globin; Haemoglobin; Hb; Hb Monza protein; HbA1c; HBB; hemoglobin; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin beta chain; hemoglobin beta subunit; Hemoglobin subunit alpha; Hemoglobin subunit beta; hemoglobin, alpha 1; hemoglobin, beta; sickle beta-hemoglobin; unnamed protein product; unstable hemoglobin; hemoglobin 'Louisville'
Gene Aliases: beta-globin; CD113t-C; ECYT6; ECYT7; HBA-T3; HBA1; HBA2; HBB; HBH; METHBA
UniProt ID: (Human) P69905, (Human) P68871
Entrez Gene ID: (Human) 3039, (Human) 3043
inflammatory response
carbon dioxide transport
oxygen transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
erythrocyte development
cellular oxidant detoxification
regulation of blood pressure
positive regulation of nitric oxide biosynthetic process
renal absorption
platelet aggregation
regulation of blood vessel diameter
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support