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Citas y referencias (17)
Invitrogen™
Vancomicina, conjugado BODIPY™ FL (vancomicina BODIPY™ FL)
Fluorescente verde
| Número de catálogo | Cantidad |
|---|---|
| V34850 | 100 μg |
Número de catálogo V34850
Precio (MXN)
-
Cantidad:
100 μg
La vancomicina BODIPY™ FL, que contiene un solo colorante BODIPY™ por molécula de vancoimicina, es un análogo verde fluorescente de este importante antibiótico, que es activo contra las bacterias grampositivas, incluidos los enterococos. Aunque no se ha informado de su actividad biológica, puede ser útil para detectar los sitios de unión y transporte de vancomicina, para ensayos de polarización de fluorescencia y para el estudio y la detección de enterococos resistentes a la vancomicina.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Excitación/emisión504/511 nm
Tipo de etiquetaTintes BODIPY
Fórmula molecularC80H88BF2Cl2N11O25
Peso molecular1723.35
Línea de productosBODIPY
Cantidad100 μg
Almacenamiento recomendadoAlmacenar en el congelador (de -5 °C a -30 °C) y proteger de la luz.
Condiciones de envíoTemperatura ambiente
Forma físicaSólido
Tipo de productoAntibiótico
Unit Size100 µg
Citations & References (17)
Citations & References
Abstract
Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane.
Journal:Proc Natl Acad Sci U S A
PubMed ID:19017791
'Cell wall peptidoglycan-anchored surface proteins are essential virulence factors in many gram-positive bacteria. The attachment of these proteins to the peptidoglycan is achieved through a transpeptidation reaction, whereby sortase cleaves a conserved C-terminal LPXTG motif and covalently attaches the protein to the peptidoglycan precursor lipid II. It is unclear how
Polar localization of virulence-related Esx-1 secretion in mycobacteria.
Journal:PLoS Pathog
PubMed ID:19180234
'The Esx-1 (type VII) secretion system is critical for virulence of both Mycobacterium tuberculosis and Mycobacterium marinum, and is highly conserved between the two species. Despite its importance, there has been no direct visualization of Esx-1 secretion until now. In M. marinum, we show that secretion of Mh3864, a novel
Use of confocal microscopy to analyze the rate of vancomycin penetration through Staphylococcus aureus biofilms.
Journal:Antimicrob Agents Chemother
PubMed ID:15917548
'When bacteria assume the biofilm mode of growth, they can tolerate levels of antimicrobial agents 10 to 1,000 times higher than the MICs of genetically equivalent planktonic bacteria. The properties of biofilms that give rise to antibiotic resistance are only partially understood. Inhibition of antibiotic penetration into the biofilm may
Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics.
Journal:Proc Natl Acad Sci U S A
PubMed ID:16832063
'The peptidoglycan (PG) layers surrounding bacterial cells play an important role in determining cell shape. The machinery controlling when and where new PG is made is not understood, but is proposed to involve interactions between bacterial actin homologs such as Mbl, which forms helical cables within cells, and extracellular multiprotein
Fluorescence ratio imaging microscopy shows decreased access of vancomycin to cell wall synthetic sites in vancomycin-resistant Staphylococcus aureus.
Journal:Antimicrob Agents Chemother
PubMed ID:17646417
'A new method of fluorescence ratio imaging microscopy was used to compare the in vivo binding capacity and the access of a fluorescent derivative of vancomycin to the cell wall synthetic sites in isogenic pairs of vancomycin-susceptible and -resistant laboratory mutants and vancomycin-intermediate and -susceptible clinical isolates of Staphylococcus aureus.