Isolectin GS-IB₄ is a 114,000-dalton glycoprotein that is part of a family of five tetrameric type I isolectins (IA₄, IA₃B, IA₂B₂, IAB₃, and IB₄) isolated from the seeds of the tropical African legume Griffonia simplicifolia. The A subunit prefers N-acetyl-D-galactosamine end groups while the B subunit is selective for terminal a-D-galactosyl residues. The far-red fluorescent Alexa Fluor™ 647 isolectin GS-IB₄ conjugate can be used in fluorescence microscopy or flow cytometry.

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