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Proteintech
NDE1 Polyclonal Antibody
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Product Details
10233-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NDE1 Fusion Protein Ag0336 (41-282 aa encoded by BC001421)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human NDE1.
Immunogen sequence: EGSREYEAE LETQLQQIET RNRDLLSENN RLRMELETIK EKFEVQHSEG YRQISALEDD LAQTKAIKDQ LQKYIRELEQ ANDDLERAKR ATIMSLEDFE QRLNQAIERN AFLESELDEK ENLLESVQRL KDEARDLRQE LAVQQKQEKP RTPMPSSVEA ERTDTAVQAT GSVPSTPIAH RGPSSSLNTP GSFRRGLDDS TGGTPLTPAA RISALNIVGD LLRKVGALES KLASCRNLVY DQS (41-282 aa encoded by BC001421)
Target Information
NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; nuclear distribution gene E homolog 1; Nuclear distribution protein nudE homolog 1; NudE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; rNudE; unnamed protein product
Gene Aliases: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS4; MHAC; mNudE; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1, (Rat) Q9ES39, (Mouse) Q9CZA6
Entrez Gene ID: (Human) 54820, (Rat) 83836, (Mouse) 67203
establishment of mitotic spindle orientation
neuron migration
microtubule nucleation
chromosome segregation
mitotic centrosome separation
neuroblast proliferation
cell migration
cerebral cortex development
forebrain development
microtubule organizing center organization
vesicle transport along microtubule
centrosome duplication
cell division
establishment of chromosome localization
centrosome localization
nervous system development
cell differentiation
cell cycle
mitotic nuclear division
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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