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Proteintech
Cathepsin H Polyclonal Antibody
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Product Details
10315-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cathepsin H Fusion Protein Ag0361 (58-289 aa encoded by BC002479)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FASNWRKIN AHNNGNHTFK MALNQFSDMS FAEIKHKYLW SEPQNCSATK SNYLRGTGPY PPSVDWRKKG NFVSPVKNQG ACGSCWTFST TGALESAIAI ATGKMLSLAE QQLVDCAQDF NNHGCQGGLP SQAFEYILYN KGIMGEDTYP YQGKDGYCKF QPGKAIGFVK DVANITIYDE EAMVEAVALY NPVSFAFEVT QDFMMYRTGI YSSTSCHKTP DKVNHAVLAV GYG (58-289 aa encoded by BC002479)
Target Information
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: aleurain; Cat H; CATH; Cathepsin B3; Cathepsin BA; CTSH; N-benzoylarginine-beta-naphthylamide hydrolase; Pro-cathepsin H; protease; unnamed protein product
Gene Aliases: ACC-4; ACC-5; ACC4; ACC5; AL022844; CPSB; CTSH
UniProt ID: (Human) P09668, (Rat) P00786, (Mouse) P49935
Entrez Gene ID: (Human) 1512, (Rat) 25425, (Mouse) 13036
endopeptidase activity
aminopeptidase activity
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
peptidase activity
cysteine-type peptidase activity
cysteine-type endopeptidase activator activity involved in apoptotic process
peptidase activator activity involved in apoptotic process
hydrolase activity
HLA-A specific activating MHC class I receptor activity
kininogen binding
identical protein binding
macromolecular complex binding
thyroid hormone binding
protein complex binding
protein self-association
cysteine protease
metanephros development
T cell mediated cytotoxicity
adaptive immune response
immune response-regulating signaling pathway
proteolysis
apoptotic process
immune response
spermatogenesis
positive regulation of gene expression
positive regulation of epithelial cell migration
neuropeptide catabolic process
bradykinin catabolic process
antigen processing and presentation
positive regulation of cell migration
zymogen activation
protein destabilization
response to retinoic acid
membrane protein proteolysis
surfactant homeostasis
proteolysis involved in cellular protein catabolic process
dichotomous subdivision of terminal units involved in lung branching
ERK1 and ERK2 cascade
cellular response to thyroid hormone stimulus
lysosomal protein catabolic process
response to odorant
positive regulation of apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of peptidase activity
negative regulation of apoptotic process
positive regulation of angiogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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