Search
Proteintech
CUL4A Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
10693-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CUL4A Fusion Protein Ag1030 (460-759 aa encoded by BC008308)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RLLVGKSAS VDAEKSMLSK LKHECGAAFT SKLEGMFKDM ELSKDIMVHF KQHMQNQSDS GPIDLTVNIL TMGYWPTYTP MEVHLTPEMI KLQEVFKAFY LGKHSGRKLQ WQTTLGHAVL KAEFKEGKKE FQVSLFQTLV LLMFNEGDGF SFEEIKMATG IEDSELRRTL QSLACGKARV LIKSPKGKEV EDGDKFIFNG EFKHKLFRIK INQIQMKETV EEQVSTTERV FQDRQYQIDA AIVRIMKMRK TLGHNLLVSE LYNQLKFPVK PGDLKKRIES LIDRDYMERD KDNPNQYHYV A (460-759 aa encoded by BC008308)
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; Cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753; ubiquitin E3 ligase; unnamed protein product
Gene Aliases: 2810470J21Rik; AW495282; CUL4A
UniProt ID: (Human) Q13619, (Mouse) Q3TCH7
Entrez Gene ID: (Human) 8451, (Mouse) 99375
G1/S transition of mitotic cell cycle
in utero embryonic development
DNA repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
spermatogenesis
cell proliferation
positive regulation of cell proliferation
protein ubiquitination
hemopoiesis
negative regulation of granulocyte differentiation
developmental process
cellular response to UV
somatic stem cell population maintenance
mRNA cleavage involved in gene silencing by miRNA
T cell activation
ribosome biogenesis
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
rhythmic process
regulation of protein metabolic process
type I interferon signaling pathway
intrinsic apoptotic signaling pathway
base-excision repair, AP site formation via deaminated base removal
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
positive regulation of G1/S transition of mitotic cell cycle
regulation of DNA damage checkpoint
regulation of nucleotide-excision repair
viral process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support