Search
Proteintech
MYOT Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
10731-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYOT Fusion Protein Ag1112 (191-498 aa encoded by BC005376)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Amount
27 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can detect both of isoforms around 57 kDa and 35 kDa.
Immunogen sequence: GPQNAAAVF QAQDDSGAQD SQQHNSEHAR LQVPTSQVRS RSTSRGDVND QDAIQEKFYP PRFIQVPENM SIDEGRFCRM DFKVSGLPAP DVSWYLNGRT VQSDDLHKMI VSEKGLHSLI FEVVRASDAG AYACVAKNRA GEATFTVQLD VLAKEHKRAP MFIYKPQSKK VLEGDSVKLE CQISAIPPPK LFWKRNNEMV QFNTDRISLY QDNTGRVTLL IKDVNKKDAG WYTVSAVNEA GVTTCNTRLD VTARPNQTLP APKQLRVRPT FSKYLALNGK GLNVKQAFNP EGEFQRLAAQ SGLYESEEL (191-498 aa encoded by BC005376)
Target Information
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 57 kDa cytoskeletal protein; Myofibrillar titin-like Ig domains protein; Myotilin; titan-like protein; Titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin); unnamed protein product
Gene Aliases: 5530402I04Rik; LGMD1; LGMD1A; MFM3; Myo; MYOT; TTID; TTOD
UniProt ID: (Human) Q9UBF9, (Mouse) Q9JIF9
Entrez Gene ID: (Human) 9499, (Mouse) 58916, (Rat) 291605
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support