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Proteintech
MUS81 Polyclonal Antibody
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Product Details
11018-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MUS81 Fusion Protein Ag1476 (202-551 aa encoded by BC009999)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR EQKFRLKRCG LERRVYLVEE HGSVHNLSLP ESTLLQAVTN TQVIDGFFVK RTADIKESAA YLALLTRGLQ RLYQGHTLRS RPWGTPGNPE SGAMTSPNPL CSLLTFSDFN AGAIKNKAQS VREVFARQLM QVRGVSGEKA AALVDRYSTP ASLLAAYDAC ATPKEQETLL STIKCGRLQR NLGPALSRTL SQLYCSYGPL T (202-551 aa encoded by BC009999)
Target Information
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog; Structure-specific endonuclease subunit MUS81; unnamed protein product
Gene Aliases: 1200008A18Rik; AI182501; AW045863; MUS81; SLX3
UniProt ID: (Human) Q96NY9, (Rat) Q4KM32, (Mouse) Q91ZJ0
Entrez Gene ID: (Human) 80198, (Rat) 293678, (Mouse) 71711
DNA catabolic process, endonucleolytic
DNA repair
DNA recombination
response to intra-S DNA damage checkpoint signaling
DNA metabolic process
cellular response to DNA damage stimulus
resolution of meiotic recombination intermediates
telomere maintenance
double-strand break repair via break-induced replication
double-strand break repair
DNA catabolic process
replication fork processing
intra-S DNA damage checkpoint
osteoblast proliferation
resolution of mitotic recombination intermediates
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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