Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
SH2D1B Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
11871-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SH2D1B Fusion Protein Ag2454 (1-132 aa encoded by BC022407)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDLPYYHGR LTKQDCETLL LKEGVDGNFL LRDSESIPGV LCLCVSFKNI VYTYRIFREK HGYYRIQTAE GSPKQVFPSL KELISKFEKP NQGMVVHLLK PIKRTSPSLR WRGLKLELET FVNSNSDYVD VLP (1-132 aa encoded by BC022407)
Target Information
SH2D1B plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EAT-2; EWS/FLI1 activated transcript 2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain protein 1B1; SH2 domain-containing molecule EAT2; SH2 domain-containing protein 1B
Gene Aliases: EAT-2; EAT-2A; EAT2; Eat2a; RGD1563935; SH2D1B; Sh2d1b1
UniProt ID: (Human) O14796
Entrez Gene ID: (Human) 117157, (Rat) 501869, (Mouse) 26904
adaptive immune response
leukocyte activation involved in immune response
positive regulation of natural killer cell mediated immunity
innate immune response
positive regulation of innate immune response
regulation of immune response
natural killer cell inhibitory signaling pathway
positive regulation of signal transduction
peptidyl-tyrosine phosphorylation
negative regulation of interferon-gamma production
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support