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Proteintech
PRKD3 Polyclonal Antibody
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Product Details
12785-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRKD3 Fusion Protein Ag3499 (1-345 aa encoded by BC030706)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Amount
55.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSANNSPPS AQKSVLPTAI PAVLPAASPC SSPKTGLSAR LSNGSFSAPS LTNSRGSVHT VSFLLQIGLT RESVTIEAQE LSLSAVKDLV CSIVYQKFPE CGFFGMYDKI LLFRHDMNSE NILQLITSTD EIHEGDLVEV VLSALATVED FQIRPHTLYV HSYKAPTFCD YCGEMLWGLV RQGLKCEGCG LNYHKRCAFK IPNNCSGVRK RRLSNVSLPG PGLSVPRPLQ PEYVALPSEE SHVHQEPSKR IPSWSGRPIW MEKMVMCRVK VPHTFAVHSY TRPTICQYCK RLLKGLFRQG MQCKDCKFNC HKRCASKVPR DCLGEVTFNG EPSSLGTDTD IPMDID (1-345 aa encoded by B C030706)
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: nPKC-nu; Protein kinase C nu type; protein kinase C, nu; Protein kinase EPK2; Serine/threonine-protein kinase D3; unnamed protein product
Gene Aliases: 4930557O20Rik; 5730497N19Rik; EPK2; nPKC-NU; PKC-NU; Pkcnu; PKD3; PRKCN; PRKD3
UniProt ID: (Human) O94806, (Mouse) Q8K1Y2
Entrez Gene ID: (Human) 23683, (Rat) 313834, (Mouse) 75292
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
zinc ion binding
kinase activity
transferase activity
metal ion binding
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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