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          • Primary Antibodies ›
          • Cullin 1 Antibodies

          Proteintech

          CUL1 Polyclonal Antibody

          14 References
          View all (14) Cullin 1 antibodies

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          Cite CUL1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          CUL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CUL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          CUL1 Antibody (12895-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using (Product # 12895-1-AP) (CUL1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          CUL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CUL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CUL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CUL1 Antibody in Western Blot (WB)
          CUL1 Antibody in Western Blot (WB)
          CUL1 Antibody in Western Blot (WB)
          CUL1 Antibody in Western Blot (WB)
          CUL1 Antibody in Immunoprecipitation (IP)
          CUL1 Polyclonal Antibody

          Product Details

          12895-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 13 publications 13 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CUL1 Fusion Protein Ag3585 (111-462 aa encoded by BC034318)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.16 mg/mL

          Amount

          24 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: YCDSLLKKS SKNPEEAELE DTLNQVMVVF KYIEDKDVFQ KFYAKMLAKR LVHQNSASDD AEASMISKLK QACGFEYTSK LQRMFQDIGV SKDLNEQFKK HLTNSEPLDL DFSIQVLSSG SWPFQQFCTF ALPSELERSY QRFTAFYASR HSGRKLTWLY QLSKGELVTN CFKNRYTLQA STFQMAILLQ YNTEDAYTVQ QLTDSTQIKM DILAQVLQIL LKSKLLVLED ENANVDEVEL KPDTLIKLYL GYKNKKLRVN INVPMKTEQK QEQETTHKNI EEDRKLLIQA AIVRIMKMRK VLKHQQLLGE VLTQLSSRFK PRVPVIKKCI DILIEKEYLE RVDGEKDTYS YLA (111-462 aa encoded by BC034318)

          Target Information

          CUL1 gene ontology annotations related to this gene include animal organ morphogenesis; apoptotic process; cell proliferation; protein monoubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CUL-1; Cullin-1; unnamed protein product

          View more View less

          Gene Aliases: CUL1

          View more View less

          UniProt ID: (Human) Q13616

          View more View less

          Entrez Gene ID: (Human) 8454

          View more View less

          Function(s)
          protein binding protein binding, bridging ubiquitin protein ligase binding ubiquitin ligase complex scaffold activity
          Process(es)
          autophagosome assembly G1/S transition of mitotic cell cycle ubiquitin-dependent protein catabolic process protein monoubiquitination apoptotic process lysosome organization cell proliferation organ morphogenesis negative regulation of autophagy positive regulation of autophagy protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process cellular response to nutrient levels cellular response to oxidative stress TORC1 signaling positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination intrinsic apoptotic signaling pathway antiviral innate immune response positive regulation of epithelial cell apoptotic process negative regulation of TORC1 signaling
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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