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Proteintech
PIP4K2B Polyclonal Antibody
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Product Details
13218-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PIP4K2B Fusion Protein Ag4099 (1-281 aa encoded by BC027459)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSNCTSTT AVAVAPLSAS KTKTKKKHFV CQKVKLFRAS EPILSVLMWG VNHTINELSN VPVPVMLMPD DFKAYSKIKV DNHLFNKENL PSRFKFKEYC PMVFRNLRER FGIDDQDYQN SVTRSAPINS DSQGRCGTRF LTTYDRRFVI KTVSSEDVAE MHNILKKYHQ FIVECHGNTL LPQFLGMYRL TVDGVETYMV VTRNVFSHRL TVHRKYDLKG STVAREASDK EKAKDLPTFK DNDFLNEGQK LHVGEESKKN FLEKLKRDVE EILVLSPGRR IA (1-281 aa encoded by BC027459)
Target Information
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; 1-phosphatidylinositol-5-phosphate 4-kinase B; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; Phosphatidylinositol-phosphate kinase IIgamma; PI(5)P 4-kinase type II beta; PIP4KII-beta; PIPKIIgamma; PTDINS(4)P-5-kinase; PtdIns(5)P-4-kinase isoform 2-beta
Gene Aliases: AI848124; c11; PI5P4KB; PI5P4Kbeta; PIP4K2B; PIP5K2B; PIP5KIIB; PIP5KIIbeta; PIP5P4KB
UniProt ID: (Human) P78356, (Rat) O88377, (Mouse) Q80XI4
Entrez Gene ID: (Human) 8396, (Rat) 89812, (Mouse) 108083
nucleotide binding
protein binding
ATP binding
GTP binding
kinase activity
1-phosphatidylinositol-4-phosphate 5-kinase activity
1-phosphatidylinositol-5-phosphate 4-kinase activity
transferase activity
protein homodimerization activity
phosphatidylinositol kinase activity
phosphatidylinositol phosphate kinase activity
kinase
lipid metabolic process
cell surface receptor signaling pathway
regulation of autophagy
phosphatidylinositol metabolic process
negative regulation of insulin receptor signaling pathway
phosphatidylinositol phosphorylation
autophagosome-lysosome fusion
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
positive regulation of autophagosome assembly
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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