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Proteintech
Phospholemman/FXYD1 Polyclonal Antibody
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FIGURE: 1 / 14
Phospholemman/FXYD1 Antibody (13721-1-AP) in IHC (P)
Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using (Product # 13721-1-AP) (Phospholemman/FXYD1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
13721-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Phospholemman/FXYD1 Fusion Protein Ag4669 (1-92 aa encoded by BC032800)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASLGHILV FCVGLLTMAK AESPKEHDPF TYDYQSLQIG GLVIAGILFI LGILIVLSRR CRCKFNQQQR TGEPDEEEGT FRSSIRRLST RRR (1-92 aa encoded by BC032800)
Target Information
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FXYD domain-containing ion transport regulator 1; Phospholemman; phospholemman transcript variant b; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1; unnamed protein product
Gene Aliases: 0610012C17Rik; 1110006M24Rik; FXYD1; PLM; Pml
UniProt ID: (Human) O00168, (Mouse) Q9Z239, (Rat) O08589
Entrez Gene ID: (Human) 5348, (Mouse) 56188, (Rat) 58971
ion transport
potassium ion transport
sodium ion transport
chloride transport
muscle contraction
regulation of heart contraction
negative regulation of protein glutathionylation
regulation of ion transport
regulation of cardiac muscle cell membrane potential
regulation of sodium ion transmembrane transport
chloride transmembrane transport
positive regulation of sodium ion export from cell
transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
positive regulation of inorganic anion transmembrane transport
regulation of sodium ion transmembrane transporter activity
brain development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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