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Proteintech
MX1 Polyclonal Antibody
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Product Details
13750-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Chicken,
Dog,
Human,
Monkey,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MX1 Fusion Protein Ag4692 (312-662 aa encoded by BC032602)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.
Immunogen sequence: LLEEGKATV PCLAEKLTSE LITHICKSLP LLENQIKETH QRITEELQKY GVDIPEDENE KMFFLIDKIN AFNQDITALM QGEETVGEED IRLFTRLRHE FHKWSTIIEN NFQEGHKILS RKIQKFENQY RGRELPGFVN YRTFETIVKQ QIKALEEPAV DMLHTVTDMV RLAFTDVSIK NFEEFFNLHR TAKSKIEDIR AEQEREGEKL IRLHFQMEQI VYCQDQVYRG ALQKVREKEL EEEKKKKSWD FGAFQSSSAT DSSMEEIFQH LMAYHQEASK RISSHIPLII QFFMLQTYGQ QLQKAMLQLL QDKDTYSWLL KERSDTSDKR KFLKERLARL TQARRRLAQF PG (312-662 aa encoded by BC032602)
Target Information
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: IFI-78K; Influenza resistance protein; Interferon-induced GTP-binding protein Mx1; Interferon-induced protein p78; interferon-inducible protein p78; Interferon-regulated resistance GTP-binding protein MxA; Myxoma resistance protein 1; myxovirus (influenza virus) resistance 1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78; myxovirus (influenza) resistance 1 polypeptide; Myxovirus resistance protein 1; p78 protein; unnamed protein product
Gene Aliases: AI893580; IFI-78K; IFI78; lncMX1-215; MX; Mx-1; MX1; MxA
UniProt ID: (Human) P20591, (Mouse) P09922
Entrez Gene ID: (Human) 4599, (Mouse) 17857
immune system process
apoptotic process
defense response
signal transduction
response to virus
synaptic vesicle budding from presynaptic endocytic zone membrane
response to type I interferon
negative regulation of viral genome replication
innate immune response
defense response to virus
interleukin-27-mediated signaling pathway
antiviral innate immune response
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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