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Proteintech
GARS Polyclonal Antibody
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Product Details
15831-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Fruit fly,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GARS Fusion Protein Ag8322 (390-739 aa encoded by BC007755)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRLGDAVEQ GVINNTVLGY FIGRIYLYLT KVGISPDKLR FRQHMENEMA HYACDCWDAE SKTSYGWIEI VGCADRSCYD LSCHARATKV PLVAEKPLKE PKTVNVVQFE PSKGAIGKAY KKDAKLVMEY LAICDECYIT EMEMLLNEKG EFTIETEGKT FQLTKDMINV KRFQKTLYVE EVVPNVIEPS FGLGRIMYTV FEHTFHVREG DEQRTFFSFP AVVAPFKCSV LPLSQNQEFM PFVKELSEAL TRHGVSHKVD DSSGSIGRRY ARTDEIGVAF GVTIDFDTVN KTPHTATLRD RDSMRQIRAE ISELPSIVQD LANGNITWAD VEARYPLFEG QETGKKETIE E (390-739 aa encoded by BC007755)
Target Information
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 6.1.1.14; AIR synthase; AIRS; AP-4-A synthetase; Ap4A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; Diadenosine tetraphosphate synthetase; EC 2.1.2.29; GAR transformylase; GART; GARTF; Glycine--tRNA ligase; Glycyl-tRNA synthetase; Glycyl-tRNA synthetase 1; GlyRS; MGC47764; PAIS; PGFT; PRGS; storage granule protein 23; unnamed protein product
Gene Aliases: CMT2D; DSMAV; GARS; GARS1; Gena201; GENA202; GlyRS; HMN5; HMN5A; HMND5; Nmf249; RGD1559871; Sgrp23; SMAD1; SMAJI
UniProt ID: (Human) P41250, (Rat) Q5I0G4, (Mouse) Q9CZD3
Entrez Gene ID: (Human) 2617, (Rat) 297113, (Mouse) 353172
nucleotide binding
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
aminoacyl-tRNA ligase activity
glycine-tRNA ligase activity
protein binding
ATP binding
transferase activity
hydrolase activity
ligase activity
identical protein binding
protein dimerization activity
ATP:ATP adenylyltransferase activity
aminoacyl-tRNA synthetase
translational protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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