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Proteintech
PGAM1 Polyclonal Antibody
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Product Details
16126-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PGAM1 Fusion Protein Ag9110 (1-254 aa encoded by BC011678)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to PGAM1.
Immunogen sequence: MAAYKLVLI RHGESAWNLE NRFSGWYDAD LSPAGHEEAK RGGQALRDAG YEFDICFTSV QKRAIRTLWT VLDAIDQMWL PVVRTWRLNE RHYGGLTGLN KAETAAKHGE AQVKIWRRSY DVPPPPMEPD HPFYSNISKD RRYADLTEDQ LPSCESLKDT IARALPFWNE EIVPQIKEGK RVLIAAHGNS LRGIVKHLEG LSEEAIMELN LPTGIPIVYE LDKNLKPIKP MQFLGDEETV RKAMEAVAAQ GKAKK (1-254 aa encoded by BC011678)
Target Information
PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BPG-dependent PGAM 1; epididymis secretory protein Li 35; PGAM-B; PGAM1; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; Phosphoglycerate mutase isozyme B; RP11-452K12.8; similar to Homo sapiens phosphoglycerate mutase (PGAM-B) mRNA with GenBank Accession Number J04173.1; unnamed protein product
Gene Aliases: 2310050F24Rik; CDABP0006; HEL-S-35; Pgam-1; PGAM-B; PGAM1; PGAMA; Pgmut
UniProt ID: (Human) P18669, (Rat) P25113, (Mouse) Q9DBJ1
Entrez Gene ID: (Human) 5223, (Rat) 24642, (Mouse) 18648
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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