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Proteintech
ACADL Polyclonal Antibody
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Product Details
17526-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The size difference between the precursor and mature rat LCAD has been estimated to be 3 kDa on the basis of SDS-PAGE. Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD). This antibody is specific to ACADL.
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD; LCAD long chain acyl-CoA dehydrogenase; long-chain acyl-CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial; Medium-chain acyl-CoA dehydrogenase, mitochondrial; unnamed protein product
Gene Aliases: AA960361; ACAD4; ACADL; ACOADA; AU018452; C79855; LCAD
UniProt ID: (Human) P28330, (Mouse) P51174, (Rat) P15650
Entrez Gene ID: (Human) 33, (Mouse) 11363, (Rat) 25287
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
protein homodimerization activity
flavin adenine dinucleotide binding
fatty-acyl-CoA binding
palmitoyl-CoA oxidase activity
dehydrogenase
temperature homeostasis
lipid metabolic process
fatty acid metabolic process
lipid catabolic process
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
regulation of cholesterol metabolic process
positive regulation of cold-induced thermogenesis
metabolic process
cellular lipid catabolic process
protein homotetramerization
oxidation-reduction process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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