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Proteintech
MYLK2 Polyclonal Antibody
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Product Details
21173-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYLK2 Fusion Protein Ag15424 (1-300 aa encoded by BC069627)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Amount
61.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATENGAVE LGIQNPSTDK APKGPTGERP LAAGKDPGPP DPKKAPDPPT LKKDAKAPAS EKGDGTLAQP STSSQGPKGE GDRGGGPAEG SAGPPAALPQ QTATPETSVK KPKAEQGASG SQDPGKPRVG KKAAEGQAAA RRGSPAFLHS PSCPAIISSS EKLLAKKPPS EASELTFEGV PMTHSPTDPR PAKAEEGKNI LAESQKEVGE KTPGQAGQAK MQGDTSRGIE FQAVPSEKSE VGQALCLTAR EEDCFQILDD CPPPPAPFPH RMVELRTGNV SSEFSMNSKE ALGGGKFGAV C (1-300 aa encoded by BC069627)
Target Information
MYLK2 (skMLCK) is a calcium/calmodulin-dependent serine/threonine kinase expressed exclusively in adult skeletal muscle. MYLK2 encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MLCK2; myosin light chain kinase 2, skeletal muscle; Myosin light chain kinase 2, skeletal/cardiac muscle
Gene Aliases: 9830004H17Rik; BB138278; KMLC; MLCK; MLCK2; MYLK2; skMLCK
UniProt ID: (Human) Q9H1R3, (Mouse) Q8VCR8
Entrez Gene ID: (Human) 85366, (Mouse) 228785
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
myosin light chain kinase activity
protein binding
calmodulin binding
ATP binding
kinase activity
transferase activity
myosin light chain binding
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
striated muscle contraction
signal transduction
neuromuscular synaptic transmission
positive regulation of gene expression
skeletal muscle satellite cell differentiation
peptidyl-threonine phosphorylation
regulation of muscle filament sliding
skeletal muscle cell differentiation
protein autophosphorylation
cardiac muscle tissue morphogenesis
cardiac muscle contraction
protein phosphorylation
water transport
regulation of muscle contraction
phosphorylation
positive regulation of fast-twitch skeletal muscle fiber contraction
regulation of MAPK cascade
regulation of neuronal synaptic plasticity
synaptic vesicle transport
regulation of cell cycle
cardiac muscle cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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