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Proteintech
KIF5C Polyclonal Antibody
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Product Details
25897-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KIF5C Fusion Protein Ag23163 (143-194 aa encoded by BC110287)
Conjugate
Form
Liquid
Concentration
0.79 mg/mL
Amount
118.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AVPEDEQIS AKDQKNLEPC DNTPIIDNIA PVVAGISTEE KEKYDEEISS LYR (143-194 aa encoded by BC110287)
Target Information
Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Kinesin heavy chain isoform 5C; kinesin heavy chain member 5C; Kinesin heavy chain neuron-specific 2; Kinesin-1; kinesin-like; neuron-specific kinesin heavy chain 2
Gene Aliases: CDCBM2; Khc; KIAA0531; KIF5C; KINN; NKHC; NKHC-2; NKHC2
UniProt ID: (Human) O60282, (Mouse) P28738, (Rat) P56536
Entrez Gene ID: (Human) 3800, (Mouse) 16574, (Rat) 311024
organelle organization
microtubule-based movement
axon guidance
motor neuron axon guidance
intracellular mRNA localization
synaptic vesicle transport
mRNA transport
anterograde dendritic transport of messenger ribonucleoprotein complex
anterograde dendritic transport of neurotransmitter receptor complex
anterograde axonal protein transport
protein localization
cytoskeleton-dependent intracellular transport
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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