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NeoBiotechnologies
GBX2/Gastrulation Brain Homeobox 2 Monoclonal Antibody (GBX2/7235)
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Product Details
2637-MSM5-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2, kappa
Class
Monoclonal
Type
Antibody
Clone
GBX2/7235
Immunogen
Recombinant fragment (around aa150-350) of human GBX2 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control:Human placenta or brain.
Cellular Location: Nucleus.
Target Information
Altered expression of GBX2, part of the homeobox-containing human family of DNA-binding transcription factors, is associated with therapy failure and death in patients with multiple types of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gastrulation and brain-specific homeobox protein 2; Homeobox protein GBX-2
Gene Aliases: GBX2
UniProt ID: (Human) P52951
Entrez Gene ID: (Human) 2637
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
patterning of blood vessels
neural crest cell migration
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
axon guidance
cerebellum development
midbrain-hindbrain boundary morphogenesis
rhombomere 2 development
thalamus development
forebrain neuron development
cerebellar granule cell precursor proliferation
hindbrain development
midbrain-hindbrain boundary development
tube morphogenesis
inner ear morphogenesis
positive regulation of transcription from RNA polymerase II promoter
autonomic nervous system development
regulation of nervous system development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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