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          • Primary Antibodies ›
          • OLFM4 Antibodies

          Proteintech

          OLFM4 Polyclonal Antibody

          View all (10) OLFM4 antibodies

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          Cite OLFM4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          OLFM4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          OLFM4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          OLFM4 Antibody (28432-1-AP150UL) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using (Product # 28432-1-AP150UL) (OLFM4 antibody) at dilution of 1:1,000 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          OLFM4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OLFM4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OLFM4 Polyclonal Antibody

          Product Details

          28432-1-AP150UL

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.7 mg/mL

          Amount

          105 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Target Information

          OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; olfactoimedin; Olfactomedin-4; OLM4; tiarin; unnamed protein product

          View more View less

          Gene Aliases: bA209J19.1; GC1; GW112; hGC-1; hOLfD; OlfD; OLFM4; OLM4; pDP4; UNQ362; UNQ362/PRO698

          View more View less

          UniProt ID: (Human) Q6UX06

          View more View less

          Entrez Gene ID: (Human) 10562

          View more View less

          Function(s)
          structural molecule activity protein binding cadherin binding
          Process(es)
          immune response cell adhesion signal transduction negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of immune response positive regulation of substrate adhesion-dependent cell spreading
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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