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NeoBiotechnologies
GTF2H2/BTF2/TFIIH Basal Transcription Factor Monoclonal Antibody (PCRP-GTF2H2-1B9)
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FIGURE: 1 / 5
GTF2H2/BTF2/TFIIH Basal Transcription Factor Antibody (2966-MSM1-P1ABX) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of PFA-fixed MCF7 cells using GTF2H2, BTF2, TFIIH Basal Transcription Factor Monoclonal Antibody (Product # 2966-MSM1-P1ABX) followed by goat anti-mouse IgG-CF488 (green). Phalloidin counterstain (red)..
Product Details
2966-MSM1-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-GTF2H2-1B9
Immunogen
Recombinant full-length human GTF2H2 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; General transcription factor IIH subunit 2; general transcription factor IIH, polypeptide 2, 44kD subunit; general transcription factor IIH, polypeptide 2, 44kDa; TFIIH basal transcription factor complex p44 subunit; unnamed protein product
Gene Aliases: BTF2; BTF2 p44; BTF2P44; GTF2H2; p44; T-BTF2P44; TFIIH
UniProt ID: (Human) Q13888
Entrez Gene ID: (Human) 2966
G-protein coupled receptor internalization
DNA repair
nucleotide-excision repair
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
cellular response to DNA damage stimulus
response to UV
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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