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Invitrogen
PEBP1 Monoclonal Antibody (3E12D7)
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FIGURE: 1 / 8
PEBP1 Antibody (37-2100) in ICC/IF
Immunofluorescence analysis of PEBP1 was performed using 70% confluent log phase HCT-116 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Prostate Specific Acid Phosphatase (PASE/4LJ) Mouse Monoclonal Antibody (3721) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 con... View More
Product Details
37-2100
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3E12D7
Immunogen
Raised against the C-term of human RKIP.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis luminal protein 210; epididymis secretory protein Li 34; epididymis secretory protein Li 96; HCNPpp; hippocampal cholinergic neurostimulating peptide; KIAA0299; LDGF; MDGF; MOCA; Neuropolypeptide h3; PEBP-1; Phosphatidylethanolamine-binding protein 1; PPBP; prostatic binding protein; Prostatic-binding protein; Raf kinase inhibitor protein; Raf kinase inhibitory protein; Raf-1 inhibitor protein; Raf-1 kinase inhibitor protein; RKIP; unnamed protein product
Gene Aliases: HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; Pbp1; Pbpr; PEBP; PEBP-1; PEBP1; RKIP
UniProt ID: (Human) P30086, (Mouse) P70296
Entrez Gene ID: (Human) 5037, (Mouse) 23980
nucleotide binding
RNA binding
serine-type endopeptidase inhibitor activity
protein binding
ATP binding
lipid binding
phosphatidylethanolamine binding
enzyme binding
protein kinase binding
peptidase inhibitor activity
receptor binding
kinase binding
poly(A) RNA binding
mitogen-activated protein kinase binding
protease inhibitor
negative regulation of MAPK cascade
MAPK cascade
regulation of neurotransmitter levels
negative regulation of protein phosphorylation
regulation of the force of heart contraction
negative regulation of peptidase activity
positive regulation of cAMP-mediated signaling
positive regulation of mitotic nuclear division
sperm capacitation
positive regulation of acetylcholine metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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