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Invitrogen
TBP Monoclonal Antibody
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FIGURE: 1 / 9
TBP Antibody (49-1036) in ChIP-seq
ChIP was performed with 5 µg of the anti-TBP antibody (Product # 49-1036) on sheared chromatin from 1 million HeLaS3 cells. The IP’d DNA was analysed by QPCR with optimized PCR primer pairs for the promoters of the active GAPDH and c-fos genes, used as positive control targets, and for a region 1 kb upstream of the GAPDH promoter and the coding region of the inactive MB gene, used as negative control targets (figure A). The IP’d DNA was subsequently analysed with an Illumina Genome Analyzer. Library preparation, cluster generation and sequ... View More
Product Details
49-1036
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Immunogen
Raised against the amino-terminal domain of human TBP.
Conjugate
Form
Liquid
Concentration
8 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
<0.1% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA, RAC1, and CDC42.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC117320; MGC126054; MGC126055; RP1-191N21.3; TATA sequence-binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; tata-box-binding; TATA-box-binding protein; TBP; TFIID; TFIID core protein; Transcription initiation factor TFIID TBP subunit; unnamed protein product
Gene Aliases: GTF2D; GTF2D1; HDL4; SCA17; TBP; TBP1; TF2D; TFIID
UniProt ID: (Human) P20226, (Mouse) P29037
Entrez Gene ID: (Human) 6908, (Mouse) 21374
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, core RNA polymerase III binding
core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
TFIIB-class transcription factor binding
RNA polymerase I CORE element sequence-specific DNA binding
DNA binding
protein binding
obsolete general RNA polymerase II transcription factor activity
aryl hydrocarbon receptor binding
enzyme binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding
general transcription factor
RNA polymerase I preinitiation complex assembly
DNA-templated transcription, initiation
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription from RNA polymerase III promoter
spermatogenesis
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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